Subject: Chemistry
Book: General Chemistry
The Henderson-Hasselbalch equation approximates the pH of a buffer: pH = pKa + log([A–]/[HA]). It relates the pH of a solution to the pKa of the acid and the ratio of conjugate base ([A–]) to acid ([HA]). This equation is fundamental in buffer preparation, biological systems (e.g., blood pH buffering by bicarbonate), and acid–base titration calculations.
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